Magic Me

A couple of healthcare professionals got together during covid in 2021 to search for the most suitable preventative measure to combat with the virus. During the search, we discovered NMN, a NAD+ precursor. With extensive research and studies on NMN and NAD+, we found there is a great connection between it and our state of health.

Across the kingdom of life, an increase in intracellular levels of NAD+ triggers shifts that enhance survival, including boosting energy production and upregulating cellular repair. Numerous studies have demonstrated that boosting NAD+ levels increases insulin sensitivity, reverses mitochondrial dysfunction, and extends lifespan.

By middle age, our NAD+ levels have plummeted to half that of our youth. Taken orally, NMN is rapidly absorbed and converted to NAD+. Thus, let us take the journey of youth by taking Magicme NMN together.

The Importance of Boosting NAD+ with NMN

After water, NAD+ is the most abundant molecule in the body and is necessary for life. NAD+ is a coenzyme — a “helper” molecule that enzymes need to function. Enzymes are a specialized type of protein that make chemical reactions much faster. For example, without enzymes some biological reactions would take 2.3 billion years to finish. Thus, life would likely not exist without enzymes.  

Importantly, with age, and in cases of chronic diseases like obesity, cardiovascular disease, neurodegenerative disease, and sarcopenia (age-related muscle wasting), NAD+ declines. Thus restoring NAD+ levels under these circumstances with NAD+ precursors like NMN can potentially mitigate the ill effects of aging and even prevent or reverse chronic diseases. The anti-aging and pro-longevity effects of boosting NAD+ in both animal models and humans is currently supported by a growing body of scientific evidence.

NAD+ Activates Sirtuins

NAD+ fuels a critical class of enzymes called sirtuins. Sirtuins are what some call “guardians of the cell,” as they play an active role in repairing DNA and supporting the health of our mitochondria. Mitochondria are referred to as the powerhouse of the cell because they produce cellular energy called ATP. Unhealthy mitochondria produce less ATP, which leads to cell death. Since excessive DNA damage also leads to cell death, sirtuins promote cell survival by repairing DNA and keeping mitochondria pristine.

As David Sinclair, a Harvard geneticist and NAD+ researcher says we lose NAD+ as we age “and the resulting decline in sirtuin activity, is thought to be a primary reason our bodies develop diseases when we are old but not when we are young.” He believes that increasing NAD+ levels, including with NMN during aging may slow or reverse certain aging processes.

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